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When facing difficulties, don't lose heart.

面对困难时，不要丧失信心。

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Yet we need not lose heart over this bad habit.

然而，我们不必对这种坏习惯丧失信心。

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And any argument between us would not cause me to lose heart or feel a sense of loss.

VOA: special.2010.07.11

If you ask him if it's our people're gonna go, man will lose heart because of the theme of The Magnificent Ambersons that take you leave the way.

如果你问他我们人民将何去何从，人们会灰心丧气，因为《安巴逊家族》的,主题会让你无路可走。

麻省理工公开课 - 电影哲学课程节选

If that bank says no to you, do not lose heart.

VOA: special.2010.07.18

If you had trouble accessing the IRS Web site in February or March, you shouldn't lose heart, Lindsay says.

CNN: Sci-Tech - E-filing eases way for tardy taxpayers

And there are a lot of folks who, understandably, seeing what goes on in Washington, sometimes lose heart and they get cynical.

WHITEHOUSE: Remarks by the President at a Campaign Event

However, he said that according to recent census results, 59% of people still identified themselves as Christian, and believers should not lose heart.

BBC: Archbishop Rowan Williams delivers final new year message